Our research focuses on the combination of custom-designed photoresponsive molecules with nanomaterials to develop  photoactivatable nanoconstructs for biomedical applications. Discover more by exploring the website.

News from the Lab !

  • January 2025  – We just started to work on the 3rd funded AIRC Investigator Grant IG 
  • January 2026  – Our paper in ACS Chemical and Biomedical Imaging on double NO photorelease with double fluorescent readout is featured in the Cover Page
  • May 2026  – Our paper in  ACS Biomacromolecules on  NO photorelease with fluorescent self-reporting and its combination with doxorubicin is featured in the Cover Page
  • July 2026  – Our paper in  ACS Applied Nanomaterials on  Carbon dots for NO release and photothermia triggered by red light is featured in the Front Cover Page
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Latest Publications

Phototherapeutic β‑Cyclodextrin-Branched Polymer Releasing Nitric Oxide with Fluorescent Self-Reporting and Its Combination with Doxorubicin

M. Perez-Lloret, C. Parisi, F. Laneri, G.M. Leone. C. Barbagallo, K. Mangano, F. Nicoletti, S. Beni, M. Malanga and S. Sortino
Biomacromolecules 2026, 27, 3399-3404.

A Molecular Hybrid for Double Stepwise Nitric Oxide Photorelease with Double Fluorescence Readout in Living Cells

C. Parisi, F. Laneri, A. Di Porzio, B. Melilli, D. Aleo, A,. Randazzo, F. Quaglia and S. Sortino
ACS Chemical and Biomedical Imaging 2026, ASAP.

N‑Doped Carbon Dot-Based Nanoconjugates with Simultaneous Generation of Nitric Oxide and Singlet Oxygen for Phototherapeutic Applications

F. Laneri, C. Parisi, V. Andrigo, J. Guerra Pinto, L. C. Marcolino, J. Ferreira-Strixino, M. Natile and S. Sortino
ACS Appl. Nano Mater. 2025, 8, 13083−13091